Wegovy is quite effective at weight loss. It may very well be the most effective weight loss drug ever to hit the market, which is why Wegovy has become enormously popular and so well-known. In clinical trials, people lost, on average, about 16% of their total body weight, which translates to an impressive 40 pounds or more in most cases.
However, when anticipating Wegovy results, it’s important to be patient. Wegovy is designed for the long term, and total weight loss occurred over the course of more than a year, with the most significant weight loss occurring after being on Wegovy for at least six months.
Since Wegovy has been available, patients in the real world have been experiencing similar results to those of the clinical trials. However, it is important to realize that everyone’s struggle with weight is different, and you should discuss your weight loss potential on Wegovy with your healthcare provider.
How Effective is Wegovy as a Weight Loss Medication
Wegovy belongs to a class of drugs known as GLP-1 agonists. GLP-1 is a hormone naturally produced by your body that tells you when you are hungry and when your stomach feels full. Wegovy mimics these effects so that you eat less because your stomach feels fuller longer.
Wegovy was FDA-approved for long-term weight management in 2021. It was the first drug of its type to receive such approval for weight loss. Wegovy has been a breakthrough in weight control medications, with patients achieving remarkable weight loss.
For the most part, Wegovy’s benefits outweigh any side effects. The most common side effects of Wegovy are gastrointestinal impacts such as diarrhea, constipation, gas, nausea, vomiting, and bloating. However, most patients get over these side effects in time.
There are added benefits of Wegovy as regards weight-related conditions. Doctors and researchers have long known that there is a link between obesity and other serious health conditions like diabetes and heart disease. Losing weight via any method has been proven to help minimize the risks of these and other obesity-related conditions.
Therefore, any weight loss achieved on Wegovy could possibly reduce the risk of these conditions. But, Wegovy also has a direct positive impact on both diabetes and cardiovascular disease. The active ingredient in Wegovy, semaglutide, can help lower blood sugar and is also the key ingredient in specific medications prescribed for type 2 diabetes, such as Ozempic.
Furthermore, an exciting clinical trial has just been completed, which found evidence of a definite link between Wegovy and a lowered risk of cardiovascular disease. This very new research found that Wegovy can reduce the risk of heart attacks and strokes by 20% in adults with heart disease and obesity.
This is just one example of the ongoing research into the many benefits of Wegovy. It is definitely becoming a vital tool in the fight against obesity; still, it is important that you seek Wegovy only from a legitimate medical weight loss practitioner and only use it with proper medical supervision.
How Long Does it Take for Wegovy to Work?
Wegovy is designed to be used for long-term weight loss. The initial clinical trials, where people lost as much as 16% of their total body weight, lasted for 68 weeks. Based on the results of those trials, you can expect to lose up to 5% of your weight after about one month on Wegovy. After two months on Wegovy, you could lose up to 8%. The most significant weight loss, where patients can get up into those double digits, takes about nine months.
Let’s take a more detailed look at the week-by-week and month-by-month results you can expect when taking Wegovy.
Wegovy Results Week-by-Week/Month-by-Month
Weeks One and Two
Within your first two weeks on Wegovy, you probably will not notice any significant weight loss, but you will start to feel its effects in terms of feeling less hungry between meals and feeling fuller longer. You could expect a modest weight loss of 3 to 5 pounds.
Weeks Three and Four
As you enter your third and fourth week, completing your first month on Wegovy, you can expect to start losing 2 to 3 pounds a week, so by week four, there is a good chance you will have already lost 8 to 10 pounds or 5-10% of your initial body weight.
Wegovy Results Month-by-Month
As mentioned earlier, clinical trials have shown that people using Wegovy can expect to lose an unprecedented amount of weight over the course of a year to a year and a half. Most of that occurs the longer you are on Wegovy, and your weight loss will begin to ramp up in month two and beyond.
Months 2 to 3
Weight loss typically continues to increase in the second and third months, with an average loss of around 10-15% of body weight per month.
Months 4 to 6
This is when most patients on Wegovy reach the maximum or close to the maximum weight loss of the 16% experienced in the clinical trials.
Months 7-12
After month six, weight loss begins to taper off but will continue at a somewhat more gradual pace, with an average of 1-2% of body weight lost per month, for a total estimated weight loss of 10-20% over the course of a year.
Here is another way to look at the first 5 months on Wegovy, based on data extrapolated from our own patients on Wegovy.
| WEEK | AVG WEIGHT LOSS LBS | AVG WEIGHT LOSS % |
| 3 -5 weeks | 7.37 | 5.79% |
| 7-9 weeks | 11.72 | 6.12% |
| 11-13 weeks | 17.58 | 9.60% |
| 15-18 weeks | 26.62 | 15.46% |
| 18-21 weeks | 32.00 | 15.02 |
Of course, your results may vary, but you can expect similar week-to-week and month-by-month results on Wegovy.
Real-life experiences of patients using Wegovy
“I have only been on Wegovy now for about six weeks, but I can tell you honestly that I am really feeling a difference. My appetite is definitely less. The other night, I went out to dinner with the wife and brought home a “doggie bag.” I haven’t done that in years! I’d say I’ve already dropped at least 8 pounds or so, that’s more and faster than any other way I tried to lose, and I am really looking forward to where this gets me at the finish line.” – Tim R. Boca Raton, FL.
“Weight Watchers, Atkins, Keto, you name it, I’ve tried it. I have struggled with being at least 50 pounds overweight my whole adult life. Now, as I am over 40, it has become almost impossible to take it off and keep it off, and my doctor said my health is really at risk, so he prescribed Wegovy. I am a little over four months in the results have been remarkable. People around me say, “Rick, you look amazing.” I’m down 30 pounds, and my blood pressure is even under control!” Rick G. Hollywood, FL
“I just took my last shot of my six-month supply of Wegovy. I’ve lost more than 40 pounds and literally never feel hungry or think about food all day long like I used to. No cravings, I eat normal and healthy meals. Had some side effects at the beginning, but nothing all that terrible, and they all eventually stopped. I know I sound like a commercial, but this really is a life-changer, has been for me anyway.” – Sheila P, Ft. Lauderdale, FL.
“When I started on Wegovy, I was 6’4″ 370 pounds. Today is exactly 4 months since my first dose I’m down over 60 lbs. I’ve dropped several meds, including for blood pressure and Lasix, and potassium pills for gout. I am on 2.4 mg / weekly. I haven’t had any real issues with side effects, some heartburn and upset stomach, but all went away after the first couple of weeks. If you can get this, I couldn’t recommend it more!” Bobbie P. Dania Beach, FL.